अमूर्त

Signal transduction pathways in alcoholic liver disease

Rundk Hwaiz

Alcoholic Liver Disease (ALD) continues to be a leading cause of disease and fatality in the world, affecting millions of people each year. The liver is the primary organ in charge of ethanol metabolism. The oxidation of ethanol to acetaldehyde is the most common pathway for ethanol metabolism. The course of ALD is well-known, and it encompasses a wide range of liver disorders, from metabolic derangement through inflammation and necrosis (steatohepatitis), fibrosis and cirrhosis, and, in some cases, hepatocellular carcinoma. Alcohol use raises the risk of ALD in a dose- and time-dependent manner.