अमूर्त

Patients with traumatic brain injury: Acute deep venous thrombosis due to low vitamin D

Daniel Thomas

Venous Thromboembolism (VTE), which manifests as Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE), has been found to be more common in Traumatic Brain Injury (TBI) populations. In trauma patients coming to the emergency department with TBI, Virchow's triad (stasis, hypercoagulable condition, and endothelial damage) is prevalent. Bleeding in severe trauma promotes the release of coagulation factors, which can contribute to VTE. Physical and cognitive impairments, when combined, increase the likelihood of developing VTE. TBI patients are frequently immobile, weak, and bedridden, and they may also have additional severe injuries that enhance the risk of venous stasis. According to a 2009 research, TBI patients had a three-to-fourfold higher risk of DVT [1]. In neurosurgical patients, the Well's score and number of days in bed were found to be significant predictors of DVT development. Another study found that major general surgery and significant trauma were both high risk factors for the development of VTE, but extended bed rest was just a minor risk factor.