कार्डियोवस्कुलर और थोरैसिक सर्जरी के इतिहास

अमूर्त

Novel biological features of valvular heart disease

Akira Sinha

The biological features of the valvular heart disease with atrial fibrillation remain unknown when involving long non-coding RNAs (lncRNAs). This study performed system analysis on lncRNA and messenger RNA (mRNA) expression profiles constructed by using bioinformatics methods and tools for biological features of AF-VHD. The associations between mRNAs connected with lncRNAs and drugs were anticipated. The 620 AF-VHD-related DE lncRNAs and 452 DE mRNAs were recognized. The 3 lncRNA subgroups were screened. The 665 guidelines intervened by lncRNAs and TFs were recognized. The 9 mRNAs connected with lncRNAs had at least 1 potential medication communications, adding up to 37 medications. Of these, 9 medications focusing on 3 qualities are now known to have the option to control or set off atrial fibrillation or other cardiovascular arrhythmias. The found organic highlights of AF-VHD give establishments to additional natural examinations to all the more likely figure out the jobs of lncRNAs being developed from the valvular coronary illness (VHD) to AF-VHD.