अमूर्त

Evaluation of the toxicity of copper oxide and nanoparticles using the biochemical, hematological, and histological biomarkers in Nile tilapia, (Oreochromis niloticus)

Mohamed Yahya*

This study aimed to evaluate the toxicity of synthesized copper nanoparticles (CuO-NPs) on biochemical and histological changes in Nile tilapia. Silver nano colloids were characterized using visible and ultraviolet light spectroscopy and high-resolution transmission electron microscopy (HRTEM). The results showed that the exposure of Oreochromisniloticus to CuO-NPs (0.525 mg/L) at pH 7, 15 °C and 25 °C showed a significant decrease in the values of RBCs, hemoglobin, hydrogen, MCV, MCH and MCHC but a significant increase in WBCs The histological changes and apparent damage to the gills were more than that of the control group and the other treatments exposed to the same concentration of CuO-NPs at higher pH (9) and salinity (34 ppm) which revealed normal values and more or less gill structure. Hence it is recommended to reduce the toxicity of CuO-NPs in Oreochromisniloticus fish farms by increasing the water pH up to 9 or increasing the water salinity.