बायोमेडिकल रिसर्च


Effect of gastric bypass on intestinal flora in patients with type 2 diabetes mellitus

Kun Zhang, Lina Yang, Jiandong Bai, Yanping Liu, Jingyu Tian

Objective: To explore the effect of gastric bypass on the recent intestinal flora in patients with type 2 diabetes mellitus.

Methods: A total of 82 patients with type 2 diabetes mellitus treated in our hospital from January 2016 to January 2017 were enrolled in this study. The patients were randomly divided into two groups: 41 patients in each group. The patients in control group underwent open surgery and those in observation group were treated with gastric bypass. Recent intestinal flora, improved clinical indicators and the incidence of complications were compared between the two groups.

Results: The level of intestinal flora in type 2 diabetic patients in observation group after 15 d treatment was better than that in control group (P<0.05). The improvement of clinical indexes was more effective than that of control group (P<0.05), and the incidence of post-surgical complications in the observation group was significantly lower (P<0.05).

Conclusion: The treatment of type 2 diabetes mellitus with gastric bypass can regulate the intestinal flora, improve the clinical indexes such as blood glucose, reduce the incidence of complications and have high clinical value.